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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREPL
All Species:
32.12
Human Site:
Y634
Identified Species:
64.24
UniProt:
Q4J6C6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4J6C6
NP_001035844.1
727
83927
Y634
Q
N
I
K
P
Q
H
Y
P
S
I
H
I
T
A
Chimpanzee
Pan troglodytes
XP_001144400
727
83999
Y634
Q
N
I
K
P
Q
H
Y
P
S
I
H
I
T
A
Rhesus Macaque
Macaca mulatta
XP_001111959
727
83985
Y634
Q
N
I
K
P
Q
H
Y
P
S
V
H
I
T
A
Dog
Lupus familis
XP_531803
727
83861
Y634
Q
N
I
K
P
Q
H
Y
P
S
I
H
I
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C167
725
83176
Y632
Q
N
I
K
P
Q
H
Y
P
S
V
H
I
T
A
Rat
Rattus norvegicus
Q5HZA6
726
83463
Y633
Q
N
M
K
P
Q
H
Y
P
S
V
H
I
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521562
342
37329
P253
Y
E
N
D
Q
R
I
P
L
E
G
L
L
R
Y
Chicken
Gallus gallus
Q5ZKL5
732
84295
Y639
C
M
K
Y
I
K
N
Y
C
P
Y
H
N
I
K
Frog
Xenopus laevis
Q32N48
707
80150
Y613
Q
N
I
T
P
Q
N
Y
P
C
V
R
I
T
A
Zebra Danio
Brachydanio rerio
NP_001139088
692
78210
P599
N
I
Q
P
Q
L
Y
P
S
M
L
I
T
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780381
720
80994
Y629
H
N
L
R
S
Q
S
Y
P
S
V
L
V
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151599
784
87028
S693
F
E
A
I
S
S
Y
S
P
Y
D
N
L
A
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
96.1
N.A.
90.9
90.3
N.A.
26.5
47.5
42
37.9
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
99.7
99.5
98.3
N.A.
95
94.7
N.A.
34.5
66.6
61.4
54.8
N.A.
N.A.
N.A.
N.A.
51.4
P-Site Identity:
100
100
93.3
100
N.A.
93.3
86.6
N.A.
0
13.3
66.6
0
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
26.6
80
13.3
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
0
0
0
17
59
% A
% Cys:
9
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
9
0
0
0
0
0
50
0
0
0
0
59
0
0
0
% H
% Ile:
0
9
50
9
9
0
9
0
0
0
25
9
59
9
0
% I
% Lys:
0
0
9
50
0
9
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
9
0
0
9
0
0
9
0
9
17
17
0
0
% L
% Met:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
9
67
9
0
0
0
17
0
0
0
0
9
9
0
0
% N
% Pro:
0
0
0
9
59
0
0
17
75
9
0
0
0
0
9
% P
% Gln:
59
0
9
0
17
67
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
9
0
0
0
0
0
9
0
9
0
% R
% Ser:
0
0
0
0
17
9
9
9
9
59
0
0
0
0
9
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
9
67
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
42
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
17
75
0
9
9
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _